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Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development
Despite substantial progress in cancer microbiome research, recognized confounders and advances in absolute microbiome quantification …
Raúl Y. Tito
,
Sara Verbandt
,
Marta Aguirre Vazquez
,
Leo Lahti
,
Chloe Verspecht
,
Verónica Lloréns-Rico
,
Sara Vieira-Silva
,
Janine Arts
,
Gwen Falony
,
Evelien Dekker
,
Joke Reumers
,
Sabine Tejpar
,
Jeroen Raes
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DOI
Single-cell approaches in human microbiome research
Microbial culturing and meta-omic profiling technologies have significantly advanced our understanding of the taxonomic and functional …
Verónica Lloréns-Rico
,
Joshua A. Simcock
,
Geert R. B. Huys
,
Jeroen Raes
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DOI
Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host
Understanding the pathology of COVID-19 is a global research priority. Early evidence suggests that the respiratory microbiome may be …
Verónica Lloréns-Rico
,
Ann C. Gregory
,
Johan Van Weyenbergh
,
Sander Jansen
,
Tina Van Buyten
,
Junbin Qian
,
Marcos Braz
,
Soraya Maria Menezes
,
Pierre Van Mol
,
Lore Vanderbeke
,
Christophe Dooms
,
Jan Gunst
,
Greet Hermans
,
Philippe Meersseman
,
CONTAGIOUS collaborators
,
Els Wauters
,
Johan Neyts
,
Diether Lambrechts
,
Joost Wauters
,
Jeroen Raes
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DOI
Benchmarking microbiome transformations favors experimental quantitative approaches to address compositionality and sampling depth biases
While metagenomic sequencing has become the tool of preference to study host-associated microbial communities, downstream analyses and …
Verónica Lloréns-Rico
,
Sara Vieira-Silva
,
Pedro J. Gonçalves
,
Gwen Falony
,
Jeroen Raes
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Code
DOI
Endogenous IFNB expression predicts outcome in critical patients with COVID-19
Although the subject of intensive preclinical and clinical research, controversy on the protective versus deleterious effects of …
Soraya Maria Menezes
,
Marcos Braz
,
Verónica Lloréns-Rico
,
Joost Wauters
,
Johan Van Weyenbergh
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DOI
Determination of the gene regulatory network of a genome-reduced bacterium highlights alternative regulation independent of transcription factors
Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma …
Eva Yus
,
Verónica Lloréns-Rico
,
Sira Martínez
,
Carolina Gallo
,
Hinnerk Eilers
,
Cedric Bloetz
,
Joerg Stuelke
,
Maria Lluch-Senar
,
Luis Serrano
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Tracking humans and microbes
The Human Microbiome Project put the health-associated microbes found in humans on centre stage. The project’s second phase shows how …
Verónica Lloréns-Rico
,
Jeroen Raes
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DOI
Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community
The composition of the human gut microbiome is well resolved, but predictive understanding of its dynamics is still lacking. Here, we …
Kevin D'hoe
,
Stefan Vet
,
Karoline Faust
,
Frédéric Moens
,
Gwen Falony
,
Didier Gonze
,
Verónica Lloréns-Rico
,
Lendert Gelens
,
Jan Danckaert
,
Luc De Vuyst
,
Jeroen Raes
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DOI
Alternative transcriptional regulation in genome-reduced bacteria
Transcription is a core process of bacterial physiology, and as such it must be tightly controlled, so that bacterial cells maintain …
Samuel Miravet-Verde
,
Verónica Lloréns-Rico
,
Luis Serrano
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DOI
Insights into the mechanisms of basal coordination of transcription using a genome-reduced bacterium
Coordination of transcription in bacteria occurs at supra-operonic scales, but the extent, specificity, and mechanisms of such …
Ivan Junier
,
E Besray Unal
,
Eva Yus
,
Verónica Lloréns-Rico
,
Luis Serrano
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