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Mycoplasma pneumoniae
Determination of the gene regulatory network of a genome-reduced bacterium highlights alternative regulation independent of transcription factors
Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma …
Eva Yus
,
Verónica Lloréns-Rico
,
Sira Martínez
,
Carolina Gallo
,
Hinnerk Eilers
,
Cedric Bloetz
,
Joerg Stuelke
,
Maria Lluch-Senar
,
Luis Serrano
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Insights into the mechanisms of basal coordination of transcription using a genome-reduced bacterium
Coordination of transcription in bacteria occurs at supra-operonic scales, but the extent, specificity, and mechanisms of such …
Ivan Junier
,
E Besray Unal
,
Eva Yus
,
Verónica Lloréns-Rico
,
Luis Serrano
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Bacterial antisense RNAs are mainly the product of transcriptional noise
cis-Encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes. However, the role of most of these RNAs remains …
Verónica Lloréns-Rico
,
Jaime Cano
,
Tjerko Kamminga
,
Rosario Gil
,
Amparo Latorre
,
Wei-Hua Chen
,
Peer Bork
,
John I Glass
,
Luis Serrano
,
Maria Lluch-Senar
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Comparative “-omics” in Mycoplasma pneumoniae clinical isolates reveals key virulence factors
The human respiratory tract pathogen M. pneumoniae is one of the best characterized minimal bacterium. Until now, two main groups of …
Maria Lluch-Senar
,
Luca Cozzuto
,
Jaime Cano
,
Javier Delgado
,
Verónica Lloréns-Rico
,
Sabine Pereyre
,
Cécile Bebear
,
Luis Serrano
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Distinguishing between productive and abortive promoters using a random forest classifier in Mycoplasma pneumoniae
Distinguishing between promoter-like sequences in bacteria that belong to true or abortive promoters, or to those that do not initiate …
Verónica Lloréns-Rico
,
Maria Lluch-Senar
,
Luis Serrano
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Defining a minimal cell: essentiality of small ORF s and nc RNA s in a genome‐reduced bacterium
Identifying all essential genomic components is critical for the assembly of minimal artificial life. In the genome-reduced bacterium …
Maria Lluch‐Senar
,
Javier Delgado
,
Wei‐Hua Chen
,
Verónica Lloréns-Rico
,
Francis J O'Reilly
,
Judith AH Wodke
,
E Besray Unal
,
Eva Yus
,
Sira Martínez
,
Robert J Nichols
,
Tony Ferrar
,
Ana Vivancos
,
Arne Schmeisky
,
Jörg Stülke
,
Vera van Noort
,
Anne‐Claude Gavin
,
Peer Bork
,
Luis Serrano
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Assessing the hodgepodge of non-mapped reads in bacterial transcriptomes: real or artifactual RNA chimeras?
Background - RNA sequencing methods have already altered our view of the extent and complexity of bacterial and eukaryotic …
Verónica Lloréns-Rico
,
Luis Serrano
,
Maria Lluch-Senar
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Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution
In the bacterial world, methylation is most commonly associated with restriction-modification systems that provide a defense mechanism …
Maria Lluch-Senar
,
Khai Luong
,
Verónica Lloréns-Rico
,
Javier Delgado
,
Gang Fang
,
Kristi Spittle
,
Tyson A Clark
,
Eric Schadt
,
Stephen W Turner
,
Jonas Korlach
,
Luis Serrano
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